12 Prenatal screening for Down syndrome
نویسنده
چکیده
At the turn of the century, several Western countries introduced prenatal screening for Down syndrome. Technology became widely and easily available, and the combination of ultrasound and then blood tests made it possible to screen the entire pregnant population. For the first time in history, there was a chance of detecting, and eventually aborting, most instances of Down syndrome, and at relatively low cost. Some countries chose not to offer early screening during pregnancy, using value-based arguments, often claiming solidarity to weaker members in society. Yet, the same countries typically accepted abortion and prenatal diagnosis based on previously established maternal-age criteria. This chapter investigates and discusses from a philosophical perspective whether there is a relevant difference between offering prenatal tests to high-risk groups as opposed to the entire pregnant population. Is this an ethical question, or a matter of more effective ways to introduce and use new medical technology? To screen or not to screen, that is the question.
منابع مشابه
Down Syndrome: Current Status, Challenges and Future Perspectives
Down syndrome (DS) is a birth defect with huge medical and social costs, caused by trisomy of whole or part of chromosome 21. It is the most prevalent genetic disease worldwide and the common genetic cause of intellectual disabilities appearing in about 1 in 400-1500 newborns. Although the syndrome had been described thousands of years before, it was named after John Langdon Down who described ...
متن کاملApplication of Molecular DNA Markers (STRs) in Molecular Diagnosis of Down Syndrome in Iran
Down syndrome is one of the most common causes of mental retardation observed in approximately 1/700 live birth. The use of two or more STR markers related to chromosome 21 facilitates the diagnosis of Down syndrome within about six hours from the collection of the samples. This is the first study has been performed in Iranian population to assess the diagnostic value of using small tandem repe...
متن کاملStatistical study of 45 false negative cases of Down syndrome in the first trimester screening protocol during 2015-2016 and introduction of a new criterion (Ratio> 3.0 of free BhCG MoM/PAPP-A MoM) to increase the efficacy of first trimester screenin
Introduction: Down syndrome screening has become an important part of antenatal care and is performed for pregnant women worldwide. In this study, 45 statistically accurate cases of false negatives in the first trimester screening tests have been examined statistically, so that by paying attention to some criteria, we can find out how many of these cases can be detected and how much each criter...
متن کاملUse of a patient decision aid for prenatal screening for Down syndrome: what do pregnant women say?
BACKGROUND Patient decision aids (PtDAs) help people make difficult, values-sensitive decisions. Prenatal screening for assessing the risk of genetic conditions in the fetus is one such decision and patient decision aids are rarely used in this clinical context. We sought to identify factors influencing pregnant women's use of a patient decision aid for deciding about prenatal screening for Dow...
متن کاملOnm-13: Prenatal Care in High-Risk Pregnancies
Prenatal care is more than just health care in pregnancy. For the vast majority of women, pregnancy follows a routine course. Some women, however, have medical difficulties related to their health or the health of their baby. These women experience what is called a high-risk pregnancy. A pregnancy may be considered high-risk for a variety of reasons. Some of these include: diabetes, preeclampsi...
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تاریخ انتشار 2008